The Healing Effect of Pilocarpine Gel on Skin lesions of Pemphigus Vulgaris. AliReza Yoosefi

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center	:	Isfahan University of Medical Sciences
Document Type	:	Latin Dissertation
Language of Document	:	English
Record Number	:	102559
Doc. No	:	T9302
Call number	:	‭WR,200,Y59h,2004‬
Main Entry	:	Yoosefi, AllReza
Title & Author	:	The Healing Effect of Pilocarpine Gel on Skin lesions of Pemphigus Vulgaris. AliReza Yoosefi/علیرضا یوسفی
College	:	Schools, Medical
Date	:	, 2004
Degree	:	Medicine, MD
Page No	:	[12] p.
Abstract	:	The high rate of morbidity and mortality due to long- term use of corticosteroids in pemphigus vulgaris (PV) warrants us to find a replacement for current treatment strategies. Based on a new theory on the pathophysiology of PV,Cholinomimetics can block the process of blister formation. This study was conducted to evalute the clinical effectiveness of pilocarpine gel in the treatment of skin lesions of PV. In a double blind, placebo controlled study, skin erosions of PV patients were treated by either pilocarpine or placebo gel. After 15 days of treatment, epithelialization index in two groups was compared. The mean of epitheliazation index in skin lesions received pilicarpine was significantly higher than placebo group. Pilocarpine gel is dramatically effective in the treatment of PV..
Descriptor	:	1- Pemphigns- drug theraphy.- Descriptor(s): Pilocarpine
	:	Pemphigus
	:	Acne vulgaris
	:	Biopsy
	:	Gels
	:	Dermatologic Agents
	:	Hydrocortison
	:	skin care