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" Evaluation of thyroid histologic changes following fine needle aspiration "
/Mehr angiz Ghafari
; Noushin Afsharmoghadam, Diana Taheri
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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102579
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| Doc. No
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T9652
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WK,200,G411e,2005
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| Main Entry
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Ghafari, Mehrangiz
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| Title & Author
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Evaluation of thyroid histologic changes following fine needle aspiration/Mehr angiz Ghafari
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| College
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Schools, Medical
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| Date
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, 2005
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| Degree
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Pathology, Ph.D
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| Page No
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18 p.: ill( col)
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| Note
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This thesis is also a research project with project ID: 83320
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مهرانگیز غفاری
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Original Works
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| Abstract
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Title: Evaluation of thyroid histologic changes following fine needleaspiration.Introduction: Due to the introduction of fine needle aspiration(FNA) cytology to the routine clinical preoperative examination surgicalpathologists are faced with thyroid gland specimens with FNA-inducedsecondary changes. These changes can cause diagnostic difficulties andbe a source of incorrect diagnosis. This study investigates worrisomehistologic alterations following FNA of thyroid (WHAFFT).Methods: This study was performed on the samples of thyroidresection over a 2- year period. 142 cases in two groups one with historyof previous FNA and another without FNA were selected. The histologicsections of these cases were studied for WHAFFT lesions. 1'Results: WHAFFT lesions were present in 40.8 of cases withhistory of previous FNA. Acute lesions were seen in 22 and chronic in36cases. The common lesions were hemorrhage and fibrosis. Atypicalchanges, like nuclear atypia, vascular changes, capsular pseudoinvasionand metaplasia were present in 28 (48.2 ) of cases. In the controlworrisome histologic changes were seen in 4.2 . Conclusion: Considering the large number of FNA and reduction inthe number of thyroid excisions, the advantages of FNA are manifold ascompared to few diagnostic problems. Misdiagnosis can be avoided withawareness of WHAFFT lesions.4Key words: thyroid neoplasms, thyroid diseases, Fine needleaspiration, worrisome histologic alterations following FNA of thyroid..
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| Descriptor
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Thyroid Diseases
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Biopsy, Fine- Needle
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Thyroid Nodule- Diagnosis
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Hemorrhage
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Thyroid Diseases- pathology
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Cytology
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Histology
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| Added Entry
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Afsharmoghadam, Noushin, Supervisor
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Taheri, Diana, Supervisor
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| Translated Title Supplied by Cataloguer
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ارزیابی تغییرات هیستولوژیک تیروئید ناشی از آسپیراسیون سوزنی ظریف
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