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" The Preventive analgesic effect of preincisional Peritonsillar infiltation of two doses of ketamine for postoperative pain relief in children following adenotonsllectomy. A randomized, double- blind, placebo- controlled study. Majid Jamshidi "
/مجید جمشیدی
; Mehdi Sonbolestan, Azim Honarmand
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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102691
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| Doc. No
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T11341
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WV,430,J32p,2008
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| Main Entry
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Jamshidi, Majid
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| Title & Author
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The Preventive analgesic effect of preincisional Peritonsillar infiltation of two doses of ketamine for postoperative pain relief in children following adenotonsllectomy. A randomized, double- blind, placebo- controlled study. Majid Jamshidi/مجید جمشیدی
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| College
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Schools, Medical
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| Date
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, 2008
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| Degree
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Otolaryngology, Speciality
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8 p.: tab.
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| Note
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This thesis is a also a research project with project ID 286157
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| Note
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Orginal Works
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| Abstract
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Background: In literature, the use of ketamine for the preventative analgesia in the management of postoperative pain is controversial. The purpose of the present study was the clinical assessment of the efficacy of preincisional peritonsillar infiltration of two doses of ketamine on postoperative pain relief compared with peritonsillar saline in children undergoing adenotonsillectomy. Methods/materials: Seventy-five ASA physical status I and II patients, aged 3-12 years, scheduled for adenotonsillectomy were enrolled in this randomized, double-blind, placebo-controlled study. Patients were divided into three groups of 25 each and received a local peritonsillar infiltration of 0.9 saline (group S), ketamine 0.5 mg.kg-1 (group K1), or ketamine 1 mg.kg-1 (group K2). All medications were 2 ml in volume which was applied 1 ml per tonsil 3 min prior to tonsillectomy. The Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) and Wilson sedation scale were used to evaluate pain levels and sedative conditions, respectively.Results: Group S had significantly higher CHEOPS scores than group K1 and K2. Both K1 and K2 groups had comparable scores, which were not statistically significant (P > 0.05). During 24 h after surgery, 16 patients in group S and no patients in groups K1 or K2 needed analgesics (P < 0.001). Conclusions: A 0.5 or 1 mg.kg-I dose of ketamine given at approximately 3 min before surgery by peritonsillar infiltration provides efficient pain relief during 24 h after surgery without side-effects in children undergoing adenotonsillectomy. Keywords: ketamine; adenotonsillectomy; pain; postoperative.
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| Descriptor
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1. Tonsillectomy.- Descriptors: Tonsillectomy
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Pain, Postoperative- drug therapy
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Ketamine
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Analgesics
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| Added Entry
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Sonbolestan, Mehdi, Supervisor
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Honarmand, Azim, Supervisor
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| Translated Title Supplied by Cataloguer
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بررسی تاثیر انفیلتراسیون کتامین در بستر لوزه قبل از شروع عمل در پیشگیری از درد بعد از عمل
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