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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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102709
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| Doc. No
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T11373
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| Call number
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WL,355,S115a,2007
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| Main Entry
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Saberi, Alia
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| Title & Author
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Association Between Chlamydia Pneumoniae Infection seropositivity and Carotid Atheroscleotic Plaque. Alia Saberi/عالیا صابری
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| College
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Schools, Medical
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| Date
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, 2007
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| Degree
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Neurology, Speciality
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| Page No
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11 P.: tab
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| Note
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This thesis a also a research project with project ID 384187
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| Note
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Orginal Works
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| Abstract
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Background and purpose: Several studies have suggested association between Chlamydia pneumonia infection and atherosclerosis. This study was designed to investigate the association between this organism and atherosclerotic plaque formation in right and left common carotid arteries (CCAs) and extracranial portion of internal carotid arteries (ICAs). Methods: Antibodies to Chlamydia pneumoniae (IgA and IgG) were measured and compared in 42 patients who had plaque(s) in at least one of CCAs or ICAs (that were detected by duplex ultrasound) and 82 patients without any plaque in these arteries. Cp.IgG and Cp.IgA titers over than. 1.10 ISR was defined to be positive. Results: We found that 6.1 of control subjects and 16.7 of our cases were Cp.IgA seropositive. The difference between these two groups was prominent but was not statistically significant (p=0.104). 4.2 of females without atherosclerotic plaque and 31.6 of them with plaque were Cp.IgA seropositive; this difference is statistically significant (p=0.005). There wasn't any significant difference in seropositivity of Cp.IgG between case and control subjects and so in men and women groups with and without plaque. Conclusion: Cp.IgA is 'a predictor of atherosclerosis in women, but Cp.IgG hasn't a predictive value for plaque formation in any gender. Ke, words: Atherosclerotic Plaque, Chlamydia pneumoniae, serum antibody.
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| Descriptor
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1. Carotid Artery Diseases.- Discriptors: Carotid Artery Diseases
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Chlamydia Pneumoniac
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Chlamydia Infection
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Carotid Artery, Internal
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Artherosclerosis
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IgG
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| Added Entry
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Ashtari, Fereshteh, Supervisor
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Shayghannejag, Vahid, Supervisor
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Khosravi, Alireza, Supervisor
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Sherkat, Roya, Supervisor
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| Translated Title Supplied by Cataloguer
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بررسی تاثیر عفونت کلامیدیا پنومونیه بر ایجاد پلاک آترواسکلروتیک در شریان کاروتید
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http://elib.mui.ac.ir/site/catalogue/102709
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