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" The comparison of preemptive effects of propofol, remifentanil and ketamine on post-operative pain scores and analgesic requirements in elective lower abdominal surgery under general anesthesia: A randomized, double-blinded study "
/امیرمحمد ابطحی
; Khosrou Naghibi
; Parviz Kashefi
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103321
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| Doc. No
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T14650
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| Call number
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WO,184,A164c,2013
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| Main Entry
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Abtahi, Amir Mohammad
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| Title & Author
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The comparison of preemptive effects of propofol, remifentanil and ketamine on post-operative pain scores and analgesic requirements in elective lower abdominal surgery under general anesthesia: A randomized, double-blinded study/امیرمحمد ابطحی
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| College
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Schools, Medical
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| Date
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, 2013
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| Degree
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Medicine, MD
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| Page No
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25 p.: diag, tab
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| Note
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This is a research dissertation with project ID: 390154
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| Note
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Orginal works
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| Abstract
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In this randomized, double-blinded study, we investigated the preemptive effects of propofol, remifentanil or ketamine on post-operative pain scores and analgesic requirements in elective lower abdominal surgeries under general anesthesia during the first 24 h of post-operative period. Seventy five patients, American Society of Anesthesiologists physical status I or II candidate for elective lower abdominal surgery under general anesthesia were randomized to three groups (25 each). According to their allocated group, patients received either propofol 0.25 mg/kg, remifentanil 0.25 mic/kg or ketamine 0.3 mg/kg as preemptive analgesia immediately after the induction of general anesthesia. Post-operative pain scores with a numerical rating scale (visual analogue scale 0-10) were assessed and analgesic requirements and side-effects were compared through analysis using the SPSS version 18 in the post-operative period; post-anesthesia care unit 2, 6, 12 and 24 h. Patients' demographics were similar in all groups. The pain scores were significantly lower in remifentanil group immediately after recovery and also at 2 and 6 h post-operatively, but it reversed at 12 and 24 h after recovery comparing with propofol and ketamine. However, the mean of administered morphine in the first 24 h was significantly lower in propofol group (18.97+- 6.6) comparing with remifentanil group (21.96+- 6.55) and ketamine group (24.26 +- 5.84) (P value, 0.01). Prophylactic preemptive single dose of intravenous (IV) 0.25 mg/kg propofol significantly decreased post-operative analgesia requirements comparing with IV 0.3 mg/kg ketamine or 0.25 إg/kg remifentanil..
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| Descriptor
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1. Pain, Postoperative.- Descriptors: Pain, Postoperative
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Analgesics
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Propofol
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Abdomen- surgery
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| Added Entry
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Naghibi, Khosrou, Supervisor
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Kashefi, Parviz, Advisor
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| Translated Title Supplied by Cataloguer
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بررسی مقایسهای تاثیر پره امپتیو سه داروی پروپوفول - رمی فنتانیل و کتامین بر درد و میزان مخدر مصرفی بعد از عمل جراحی ناحیه تحتانی شکم تحت بیهوشی عمومی
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