Effect of omega-3 supplementation on inflammatory parameters in patients on chronic ambulatory peritoneal dialysis

/رضا ابراهیمی کرد آسیابی، فیروزه معین زده; ; Afsoon Emami Naini

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center	:	Isfahan University of Medical Sciences
Document Type	:	Latin Dissertation
Language of Document	:	English
Record Number	:	103328
Doc. No	:	T14725
Call number	:	‭WJ,378,E16e,2014‬
Main Entry	:	Ebrahimi Kord Asiabi, Reza
Title & Author	:	Effect of omega-3 supplementation on inflammatory parameters in patients on chronic ambulatory peritoneal dialysis/رضا ابراهیمی کرد آسیابی، فیروزه معین زده
College	:	Schools, Medical
Date	:	, 2014
Degree	:	Medicine, MD
Page No	:	18 p.
Note	:	This is a research dissertation with project ID: 391350
Note	:	Orginal works
Abstract	:	End stage renal disease (ESRD) is a state of micro inflammation that attenuate patient`s life span and quality of life. inflammatory markers like interlukin 6 (IL-6) and C-reactive protein (CRP) can predict inflammatoryu state in ESRD patients. Dietary limitations are risk factords for omega-3 deficiency in these patients. omega-3 supplementation is an attractive material that proposed in inflammation modulation. the aim of this study is evaluation of effect of omega-3 supplementation on Il-6 and CRP level in chronic ambulatory peritoneal dialysis (CAPD) patients. this randomized controlled double-blind clinical trial is performed in 40 CAPD patients in two academic hospital in Isfahan, IRAN. ome group receved 1000mg omega-3 capsule (each capsule contain 180mg eicosapentanoic and 120 mg dosahexanoic acid) three times a day orally for 8 weeks (n=20) and the other matched group by placebo (n=20). serum level of IL-6 and quantitative CRP (Q_CRP) were measured in beginning and the end of the study. finally all data were analyzed by SPSS version 18. mean age of patients was 53 yerars old in omega-3 group patients and 54 years old in lacebo group. there were not any differences in CRP and IL-6 level in the beginning and the end of study between two groups. Omega-3 supplementation did not effect on infalmmatory markers in CAPD patients after 8 weeks.
Descriptor	:	1.peritoneal Dialysis .- Descriptors: peritoneal Dialysis
	:	Eicosapentaenoic Acid
Added Entry	:	Emami Naini, Afsoon, Supervisor
Translated Title Supplied by Cataloguer	:	بررسی اثر ا مگا‭ ۳ ‬بر روی فاکتورهای التهابی ‭(IL6- CRP)‬ در بیماران دیالیز صفاقی مراکز درمانی بیمارستان های الزهراء (س) و نور و حضرت علی اصغر اصفهان