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" Comparison of conventional and diffusion-weighted MRI to fine multiple sclerosis lesions in acute optic neuritis patients "
/پروانه زیراهی
; Mohammad Javad Marashi, Nazila Tayari
; Masoud Etemadifar
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103340
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| Doc. No
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T14712
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| Call number
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WN,185,Z81c,2014
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| Main Entry
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Zirahi, Parvane
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| Title & Author
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Comparison of conventional and diffusion-weighted MRI to fine multiple sclerosis lesions in acute optic neuritis patients/پروانه زیراهی
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| College
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Schools, Medical
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| Date
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, 2014
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| Degree
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Radiology, Specialty
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| Page No
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12 p.: tab.
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| Note
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This is a research dissertation with project ID: 393133
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| Note
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Orginal works
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| Abstract
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Optic neuritis (ON) is an common cause of unilateral painful visual loss on young adults. in countries with high prevalence of nultiple sclerosis (MS) most cases of ON are related to MS. the aim of the current study is to compare the diffusion-weighted MRI (DWI) and conventional MRI power to fine MS lesions and evaluate the diagnostic power of DWI according to conventional MRI in acute optic neuritis patients. in an cross-sectional study, patients with diagnosis of acute optic neuritis wer enrolled. patients with other differntial diagnosis of On were excluded. all the participants were undetgone DWI and conventioanl MRI and numbers and also area of MD lesions were defined for each patient. conventional MRI was used ad gold standard and diagnostic power of DWI was calculated. in this study 60 patients were enrolled. MS lesions were seen in 42 (70 percent) and 45 (75 percent) of patients after imaging by DWI and conventional MRI respectively. total and mean of lesion numbers reorted by DWI and conventional MRI were 182 (3.03 +- 0.32)and 173 (2.88 +-0.29) respectively and there was nbo significant difference between two type of imaging. diagnostic power analysis for DWI showed sensitivity=0.933, specificity-1.00, PPV=0.100, NPV=0.833. our results showed that both DWI and conventional MRI are nearly the same in detecting the MS lesions in early stages of ON. althoughmore studies are needed but we suggest that theere is no benefit in using both imaging methods for detecting MS lesions.
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| Descriptor
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1. Magnetic Resonance Imaging.- Descriptors: Magnetic Resonance Imaging
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Diffusion Magnetic Resonance Imaging
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Multiple Sclerosis
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Optic Neuritis
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Multiple Sclerosis
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| Added Entry
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Marashi, Mohammad Javad, Supervisor
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Tayari, Nazila, Supervisor
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Etemadifar, Masoud, Advisor
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