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" Neonatal outcomes in women with gestational diabetes mellitus treated with metformin in compare with insulin: a randomized clinical trial "
/صفیه اسحاقیان
; Safura Ruholamin, Zahra Allame
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103341
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| Doc. No
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T14700
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| Call number
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WQ,248,E75n,2013
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| Main Entry
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Eshaghian, Safieh
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| Title & Author
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Neonatal outcomes in women with gestational diabetes mellitus treated with metformin in compare with insulin: a randomized clinical trial/صفیه اسحاقیان
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| College
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Schools, Medical
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| Date
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, 2013
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| Degree
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Gynecology, Specialty
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| Page No
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23 p.: tab
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| Note
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This thesis is a also a research project with project ID 391047
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| Note
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Orginal Works
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| Abstract
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The objective of this study was to compare neonatal outcomes in women with gestational diabetes mellitus (GDM) treated with either metformin or insulin. a randomized clinical trial carried out on yera 2011 on 109 women with GDM who did not adequately control by dietary measures. they received metformin 500 mg once or twice daily or insulin 0.2 IU/kg/day initially. the dose was titrated to achieve target blood glucose values. neonatal outcomes such as hypoglycemia, birth weight, apgar score, umbilical artery pH, and hyperbilirubimemia in the 59 women who remained exclusively on metformin were compared with 50 women who treated with insulin. two groups were similar in mean fasting blood suger and postprandial measurments. throughout GDM treatment. pregnancy complications or preterm labor were not different significantly between two groups. considering neonatla outcomes between insulin and metformin groups. such as hypollycenia, birth weight, 5th min apgar score, umbilical artery pH and hyperbilirubinemia, no significant statistical differences were seen. based on these preliminary data, considering neonatal outcomes, metformin appears to be a safe as insulin in the treatment of GDM.
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| Descriptor
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1. Diabetes, Gestational.- Discriptors: Diabetes, Gestational
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Insulin
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Metformin
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Infant, Newborn
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| Added Entry
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Ruholamin, Safura, Supervisor
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Allame, Zahra, Supervisor
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| Translated Title Supplied by Cataloguer
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بررسی outcome مادری و جنینی در GDM در دو گروه درمانی متفورمین و انسولین
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