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" Correlation of intelligence quotient (IQ) in multiple sclerosis with MRI findings and retianl nerve fiber layer thickness "
/پریسا امامی اردستانی
; Fereshteh Ashtari
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103377
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| Doc. No
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T14935
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| Call number
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WL,360,E53c,2014
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| Main Entry
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Emami Ardestani, Parisa
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| Title & Author
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Correlation of intelligence quotient (IQ) in multiple sclerosis with MRI findings and retianl nerve fiber layer thickness/پریسا امامی اردستانی
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| College
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Schools, Medical
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| Date
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, 2014
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| Degree
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Neurology, Specialty
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| Page No
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23 p.: tab
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| Note
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This thesis is a research project with project ID: 392083
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| Abstract
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Multiple Sclerosis (MS) is a neurological disease in which demyelination and axonal loss leads to progressive disability. Cognition impairment is among most common complication. Studying axonal loss in the retina is a new marker for multiple sclerosis (MS). The main goal of our study was to search for correlations between MRI findings and retinal nerve fiber layer(RNFL) thickness at macula and head of optic nerve and Wechsler Adult Intelligence Scale-Revised (WAIS-R) Scores that assessed multiple domain of intelligence, to explore the relationship between changes in the RNFL thickness with intellectual and cognitive dysfunction. A prospective cross-sectional study was conducted at university hospital of kashani, Isfahan, Iran, from September to December 2013. All patients assessed with full-scale IQ on the WAIS-R. Optical coherence tomography study and brain MRI was performed in the same week for all patients. Statistical analysis with using a bivariate correlation was done by utilizing SPSS 20.0. P-value ?0.05 were the threshold of statistical significance. Examination of 100 patients was shown significant correlation between average RNFL thickness of macula and verbal IQ (p value=0.01) and full IQ (p value =0.01). There was significant correlation between brain atrophy and verbal IQ. RNFL loss was correlated with verbal IQ and full IQ.
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| Descriptor
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1. Multiple Sclerosis.- Descriptors: Multiple Sclerosis
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Cognition
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Tomography, Optical Coherence
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Intelligence
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| Added Entry
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Ashtari, Fereshteh, Supervisor
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| Translated Title Supplied by Cataloguer
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بررسی ارتباط ضخامت RNFL با میزان اختلال شناختی بیماران MS
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