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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103388
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| Doc. No
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T14998
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| Call number
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WO,184,A313i,2014
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| Main Entry
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Akbari, Saeed
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| Title & Author
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Increase in intraocular pressure is less with propofol and remifentanil than isoflurane with remifentanil during cataract surgery: A randomised controlled trial/سعید اکبری
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| College
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Schools, Medical
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| Date
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, 2014
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| Degree
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Anesthesiology, Speciality
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| Page No
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21 p.: tab, diag
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| Note
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This thesis is a research project with project ID 393285
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| Note
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Orginal Works
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| Abstract
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This double-blinded, randomised clinical trial was designed to evaluate intraocular pressure (IOP) change in cataract surgery using the combination of propofol and remifentanil or the combination of isoflurane and remifentanil. One hundred Sixty patients were randomly allocated to a maintenance anesthetic consisting of remifentanil+isoflurane (GroupI), normal saline+isoflurane (GroupII), propofol+remifentanil (GroupIII) or normal saline+propofol (GroupIV). IOP was measured at seven predefined time points, including baseline (T0), three min after the start of continuous remifentanil infusion (T2), after induction of anesthesia (T3), immediately after laryngoscopy and intubation (T4), five min after laryngoscopy (T5), immediately after the block of continuous remifentanil infusion (T6) and three min after T6 (T7). Outcomes included IOP, systole and diastole blood pressure (BP), mean arterial pressure (MAP) and heart rate (HR). The mean of IOP in Group III was lower than other groups and in group IV was higher than other groups. At time point T4 and T5 differences in the mean of IOP between groups III and IV was significantly different (P-values>0.05). The trend in changes in the mean of IOP was statistically significant among groups (P-value=0.01). The trend in changes in the mean of SBP DBP and MAP were not significantly different among groups (P-value=0.41). HR in group III was significantly lower than other groups. The trend in changes in the mean of HR was significantly different among groups (P-value=0.002). Propofol with remifentanil was more effective than placebo or adding remifentanil to isoflurane in management of IOP in cataract surgery.
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| Descriptor
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1. Postoperative Complications.- Descriptors: Intraocular Pressure
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Postoperative Complications
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Propofol
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Anesthetics, Intravenous
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Anesthesia, General
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Cataract Extraction
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| Added Entry
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Montazeri, Kamran, Supervisor
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Dehghani, Alireza, Supervisor
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Nasrollahi, Kobra, Supervisor
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Montazeri, Kamran, Counselor
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http://elib.mui.ac.ir/site/catalogue/103388
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