رکورد قبلیرکورد بعدی

" An observational study on the expression of cyclooxygenase-2 in meningioma and its correlation with tumor grade "


center : Isfahan University of Medical Sciences
Document Type : Latin Dissertation
Language of Document : English
Record Number : 103393
Doc. No : T14969
Call number : ‭QZ,380,S246o,2014‬
Main Entry : Sarmadi, Tannaz
Title & Author : An observational study on the expression of cyclooxygenase-2 in meningioma and its correlation with tumor grade/طناز سرمدی
College : Schools, Medical
Date : , 2014
Degree : Pathology, Speciality
Page No : 16 p.: tab
Note : This thesis is a research project with project ID: 391338
Abstract : the Cyclooxygemase-2 enzyme is overexpressed in different types of tumors and is known to be associated with malignant behaviour of tumors. we determined the asociation of COX-2 expression and different grades of human meningioma. this retrospective study was conducted on specimens obtained from adult patients with meningioma. meningioma was classified according to the WHO 2007 classification protocol (I, II, and III). COX-2 expression intensity was secored based on the percentage of immunopositive cells and 0:0-10 percent+1>10 percent and a part of the cell membrance; +2:.10percent and complete cell membrance; and +3:.30 percent and complete cell membrance. scores of +2 or +3 were considered as COX-2 positive. ninety meningioma cases were studied. COX-2 was positive in 25 percent (17/68), 68.4 percent (13/19) and 100 percent (3/3) of cases with tumor grade I, II and III, resectively. there was a significant correlation between tumor grade and COX-2 exression score. there is a strong association between COX-2 expression and rumoral grade in meningioma with more aggressive tumors expressing COX-2 expression with tumor recurrence and interventional studies examining the role of COX-2 inhibitors anticancer therapy of meningioma are warrated.
Descriptor : 1. Meningioma.- Descriptors: Meningioma
: Central Nervous System Neoplasms
: Meningioma
Added Entry : Mahzouni, parvin, Supervisor
Translated Title Supplied by Cataloguer : بررسی شیوع بیان مارکر ‭COX-II‬ در مننژیوما و ارتباط آن با گریدر عود تومور
کپی لینک

پیشنهاد خرید
پیوستها
عنوان :
نام فایل :
نوع عام محتوا :
نوع ماده :
فرمت :
سایز :
عرض :
طول :
An observational study on the expression of cyclooxygenas...
Tannaz Sarmadi.pdf
پایان نامه لاتین
متن
application/pdf
755.71 KB
85
85
موجودی
کتابخانه مؤیدالاطباء
نمایش کامل جزئیات | عدم نمایش جزئیات
جزئیاتمحل نگهداریشماره ثبتشناسه بازیابیجلدوضعيتتاريخ برگشت
2 - کتابخانه مؤیدالاطباء14969موجود‭‬
نظرسنجی