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" Evaluation of some related factors causing acute aortic dissection type A and comparison of clinical outcomes between two surgical methods on post operation consequences "
/مهدی محسنی بدل آبادی
; Hasan Shemirani
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103418
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| Doc. No
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T15030
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| Call number
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WG,410,M698e,2014
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| Main Entry
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Mohseni Badalabadi, Mehdi
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| Title & Author
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Evaluation of some related factors causing acute aortic dissection type A and comparison of clinical outcomes between two surgical methods on post operation consequences/مهدی محسنی بدل آبادی
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| College
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Schools, Medical
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| Date
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, 2014
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| Degree
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Cardiology, Speciality
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22 p.: tab
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| Note
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This is a research dissertation with project ID 393316
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| Abstract
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Although aortic dissection is a rare disease, it causes high level of mortality. If ascending aorta gets involved in this disease, it is known as type A. According to small number of studies about this disease in Iran, this study conducted to detect the factors related to acute aortic dissection type A, its surgery consequences and the factors affecting them. Methods: In this historical cohortstudy, all patients having acute aortic dissection type Areferring to Chamran hospital from 2006 to 2012 were studied.The impact of two surgical methods including Antegrade cerebral perfusion (ACP) and retrograde cerebral one (RCP) on surgical and long-term mortality and recurrence of dissection was determined. The relation of mortality rate and hemodynamic instability before surgery, age more than 70 years old,ejection fractionlower than 50 percent, prolonged cardiopulmonary bypass pump (CPBP) time and excessive blood transfusion, was assessed. Results: Surgery and long-term mortality and recurrence of dissection were 35.3, 30.8 and 30.4 percent.Surgical and long-term death in the patients being operated by ACP method was lower than those one being operated by RCP (P<0.001).Excessive blood transfusion and unstable hemodynamic condition had significant effect on surgical mortality (P= 0.014, 0.030 respectively).CPBP time and unstable hemodynamic condition affected long-term mortality significantly (P=0.002). Discussion:Considering gender, age and hypertension as the main risk factors, most of the patients were male, 35-65 years old and suffering from hypertension.The result found that ACP is the preferable kind of surgery in comparison with RCP according to the surgical and long-term mortality. According to importance of acute aortic dissection type A and small number of studies in this field in Iran it is suggested conducting more developed studies, in longer periods of time, getting involved control group and considering more important factors.
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| Descriptor
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1. Aortic Aneurysm .- Descriptors: Aortic Aneurysm
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Coronary Artery Disease
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Aortic Aneurysm, Thoracic
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Hypertension
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| Added Entry
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Shemirani, Hasan, Supervisor
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