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" High flow nasal cannula as a method for rapid weaning from nasal continuous positive airway pressure "
/علیرضا عشقی
; Zohreh Badiee, Majid Mohammadizadeh
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103430
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| Doc. No
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T15061
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WS280,E75h,2014
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| Main Entry
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Eshghi, Alireza
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| Title & Author
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High flow nasal cannula as a method for rapid weaning from nasal continuous positive airway pressure/علیرضا عشقی
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| College
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Schools, Medical
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| Date
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, 2014
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| Degree
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Pediatric, Speciality
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21 p.: tab
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| Note
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This thesis is a research project with project ID: 390620
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| Abstract
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Background: To compare two methods of weaning premature infants from nasal continuous positive airway pressure (NCPAP). Materials and methods: Between March and November 2012, 88 preterm infants who were stable on NCPAP of 5 cmH2O with FIO2 < 30 for minimum of 6 hours were randomly allocated to one of two groups. The high flow nasal cannula (HFNC) group received HFNC with flow of 2 L/min and FIO2=0.3 and then stepwise reduction of FIO2 and then flow. The non HFNC group was maintained on NCPAP of 5 cmH2O and gradual reduction of oxygen until they were on FIO2 =0.21 for 6 hours and we had weaned them directly from NCPAP (with pressure of 5 cm H2O) to room air. Results: No significant differences were found between 2 study groups with regards to gestational age, birth weight, apgar score at 1 and 5 minutes after birth, patent ductus arteriosus and use of xanthines. The mean duration of oxygen therapy after randomization was significantly lower in HFNC group compared to non HFNC group (20.6+/- 16.8 hours vs 49.6+/- 25.3 hours, p<0.001). Also, the mean length of hospital stay was significantly lower in HFNC group compared to non HFNC group (11.3+/- 7.8 days vs 14.8+/-8.6 days, p=0.04). The rate of successful weaning was not statistically different between two groups.Conclusion: weaning from NCPAP to HFNC could decrease duration of oxygen therapy and length of hospitalization in preterm infants.
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| Descriptor
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1.Continuous Positive Airway Pressure .- Descriptors: Continuous Positive Airway Pressure
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Catheters
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Infant, Premature
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Weaning
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| Added Entry
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Badiee, Zohreh, Supervisor
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Mohammadizadeh, Majid, Supervisor
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| Translated Title Supplied by Cataloguer
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بررسی مقایسهای دو وروش استفاده از نازال کانولا با فشار بالا با روش کاهش تدریجی FIO2 در موفقیت برای جداسازی نوزادان نارس
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