|
" Evaluation of short term result of collagen cross linking in pellucid marginl degeneration "
/بشیر ماموسی
; Hassan Razmjoo, Alireza Peyman
| center
|
:
|
Isfahan University of Medical Sciences
|
| Document Type
|
:
|
Latin Dissertation
|
| Language of Document
|
:
|
English
|
| Record Number
|
:
|
103448
|
| Doc. No
|
:
|
T15070
|
| Call number
|
:
|
WW,220,M265e,2014
|
| Main Entry
|
:
|
Mamoosa, Bashir
|
| Title & Author
|
:
|
Evaluation of short term result of collagen cross linking in pellucid marginl degeneration/بشیر ماموسی
|
| College
|
:
|
Schools, Medical
|
| Date
|
:
|
, 2014
|
| Degree
|
:
|
Ophthalmology, Speciality
|
| Page No
|
:
|
11 p.: tab.
|
| Note
|
:
|
This thesis is a research project with project ID: 392550
|
| Abstract
|
:
|
Objective: to evaluate effectiveness of collagen cross linking in pellucid marginal degeneration patients. Methods: Twenty- one eyes of 15 patients treated by collagen cross- linking were enrolled in our non-controlled clinical trial study. After evaluation of patients about inclusion and exclusion criteria, preoperative examination was done and then patients underwent CXL procedure and seen 6 months after surgery for postoperative examinations. Results: Mean preoperative log- mar uncorrected visual acuity (UCVA) was 0.63 (SE= 0.08), and mean preoperative log- mar BCVA was 0.26 (SE= 0.04). At 6 months postoperative, mean log- mar UCVA was 0.59 (SE= 0.06) and mean log- mar BCVA was 0.19 (SE= 0.02). The non-parametric test (Wilcoxon) showed reduction of log- mar BCVA was significant (P value= 0.02), but reduction of log- mar UCVA was not significant (P value= 0.5). Mean preoperative K1 was 42.23 +/- 2.85 and mean postoperative K1 significantly decreased to 41.68 +/- 2.44 (P value= 0.008). Also, mean preoperative K2 was 48.39 +/- 2.37 and mean postoperative K2 significantly reduced to 47.64 +/- 2.16 (P value= 0.002). Conclusion: Most remarkable findings of our study were improvement of visual acuity and reduction K1 and K2 parameters. Stability of other values and absence of detectable change after study period implies halting of the progression of the disease. We suggest CXL can be useful for management of PMD, but we need more studies with larger sample size and longer follow up.
|
| Descriptor
|
:
|
1. Corneal Diseases.- Descriptors: Corneal Diseases
|
|
|
:
|
Cornea
|
|
|
:
|
Eye Diseases
|
| Added Entry
|
:
|
Razmjoo, Hassan, Supervisor
|
|
|
:
|
Peyman, Alireza
|
| Translated Title Supplied by Cataloguer
|
:
|
ارزیابی نتایج کوتاه مدت تاثیر CXL بر روی بیماران PMD
|
| |