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" vasomotor reactivity comparison in multiple sclerosis patients with white matter lesions and non-multiple sclerosis subjects with white matter lesions in brain MRI "
/علی مسائلی
; Fariborz Khorvash, Mohammad Saadatnia
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103495
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| Doc. No
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T15090
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| Call number
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WL,360,M394v,2014
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| Main Entry
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Masaeli, Ali
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| Title & Author
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vasomotor reactivity comparison in multiple sclerosis patients with white matter lesions and non-multiple sclerosis subjects with white matter lesions in brain MRI/علی مسائلی
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| College
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Schools, Medical
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| Date
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, 2014
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| Degree
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Neurology, Specialty
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| Page No
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22 p.: Diag, tab.
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| Note
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This thesis is a research project with project ID: 393035
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| Abstract
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it has been recognized a close relationship between multiple sclerosis (MS) lesions and the cerebral vasculature. in this study we observed cerebrovascular vasomotor reactivity differnce between the MS patients and the non-MS migraine individuals. this prospective study was conducted on 40 patients with multuple scleroswis referring to neurology clinic of isfahan Alzahra hospital in 2012. the patients were compared with the same number of non-MS migraine individuals. both groups had white matter lesions in brain MRI. to evaluate the rate of cerebral artery vasomotor reactivity, TCD device was used and BHI was separately calculated for each MCA. main flow velocity (MFV) was determined by continuously recording of a perod of 5 minutes of breathing the air in the room. the obtained data were analyzed using SPSS software version 18 and T-test, chi-square and ANOVA tests. the mean values of MFV at rest was not significantly different between cases and control groups but difference between cases and control groups in MFV apnea was significant. BHI in the control group was 0.79+/-0.26 and in the case group was 0.93+/-0.20 and these differences was found to be significant. the mean of BHI and cerebral vasomotor reactivity in multiple sclerosis patients was more than the mon-MS migraine individulas, although mechanism of thes process is still remains unknown.
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| Descriptor
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1. Multiple Sclerosis.- Descriptors: Multiple Sclerosis
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White Matter
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Magnetic Resonance Imaging
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| Added Entry
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Khorvash, Fariborz, Supervisor
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Saadatnia, Mohammad, Supervisor
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