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" The evaluation of prophylactic effects of intrathecal meperidine and intrvenous ondansetron on shivering in patients undergoing lower extremity orthopedic surgery under spinal anesthesia "
/زهرا نگهبان
; Mohammad Reza safavi Homami, azim Honarmand
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103510
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| Doc. No
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T15153
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| Call number
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WO,184,N384e,2014
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| Main Entry
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Negahban, Zahra
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| Title & Author
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The evaluation of prophylactic effects of intrathecal meperidine and intrvenous ondansetron on shivering in patients undergoing lower extremity orthopedic surgery under spinal anesthesia/زهرا نگهبان
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| College
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Schools, Medical
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| Date
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, 2014
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| Degree
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Medicine, M.D
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14 p.: tab.
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| Note
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This thesis is a research project with project ID:390570
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| Abstract
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Intraoperative hypothermia is a common problem with anesthesia. Spinal anesthesia,the same as general anesthesia, affects the process of temperature regulation. The aim of this study was to compare the prophylactic effect of intravenous ondansetron with intrathecal meperidine on prevention of shivering during spinal anesthesia in patients underwent orthopedic surgery of the lower limb. In this study, 120 patients with ASA (American society of anesthesiologists) physical status I to II, between the ages 16-65 were randomized into three groups. Group O and Group M were given intravenous ondansetron 8 mg and intrathecal meperidine 0.2 mg/kg, before spinal anesthesia, respectively. Group C received intravenous saline 0.9 percent. The core and ambient temperatures, the incidence and intensity of shivering, blood pressure, heart rate and maximum level of sensory block were recorded. Shivering was observed in 15 percent, 2.5 percent and 37.5 percent of patients in groups O, M and C, respectively. There was a significant difference between group O and M compared to group C (Group O P = 0.023 vs group C, group M P = 0.00 vs group C and group M P = 0.049 vs group O). Shivering incidence and intensity in group M was significantly lower than group O (P = 0.049 and P = 0.047, for incidence and intensity, respectively). Twenty two patients required additional intravenous meperidine among which 15 patients were from group C (37.5 percent), 6 patients from group O (15 percent) and 1 patient from group M (2.5 percent). We concluded that intrathecal meperidine and intravenous ondansetron comparably can decrease intensity and incidence of shivering compared to control group as well as decreasing the requirement to additional doses of meperidine for shivering control without any hemodynamic side effect.
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| Descriptor
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1. Postoperative Complications.- Descriptors: Postoperative Complications
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Anesthesia, Spinal
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Orthopedics
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Ondansetron
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Meperidine
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Hypothermia
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| Added Entry
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Safavi Homami, Mohammad Reza, Supervisor
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Honarmand, Azim, Supervisor
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| Translated Title Supplied by Cataloguer
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بررسی مقایسهای تاثیر مپریدین اینتراتکال با اندانسترون وریدی بر لرز به دنبال بی حسی اسپینال در جراحی های ارتوپدی اندام تحتانی
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