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" Effect of preemptive multimodal combination of gabapentin and acetaminophen on limbs orthopedic postoperative pain "
/شیما غفوری
; Parviz Kashefi
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103515
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| Doc. No
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T15156
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WO,184,G411e,2014
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| Main Entry
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Ghafouri, Shima
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| Title & Author
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Effect of preemptive multimodal combination of gabapentin and acetaminophen on limbs orthopedic postoperative pain/شیما غفوری
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| College
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Schools, Medical
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| Date
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, 2014
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| Degree
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Medicine, M.D
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| Page No
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11 p.: tab., Diag
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| Note
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This thesis is a research project with project ID: 390524
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| Abstract
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to reduce or treat pain after surgery, several methods have been evaluated. but any study was done to comparison multimodal combination effects of gabapentin and acetaminophen on limbs orthopedic surgeries. this study aimed to determine the effect of preemptive multi-modal combination of gabapentin and acetaminophen on limbs rothopedic postoperative pain under geneta anesthesia was condected. in a clinical trial study, 140 patients under limb orthopedic surgeries were selected and randomly divided in the 4 groups receiving acetaminophen and gabapentn. gabapentin, acetaminophen and placebo. after extubation pain scores (visual analouge scale) VAS that previously had been taught to patients, was used to determine recovery time and recovery rate of opium consumption were recorded. data was analyzed by SPSS22 software. the men pain intensity at all times between the four groups was different. the pain intensity in both groups of gabapentin and gabapentin+ acetaminophen had no significant difference. in other cases, the difference between groups was significant. thus the pain intensity in placbo group was significantly different from the other three groups and the group receining gabapentin was significantly different from acetaminophen and placebo groups. use of gabapentin as a premedication has suitable effect fro decreasign postoperative pain and reduces the need for the opium to reduce pain, while using multi -modal acetaminophen wth gabapentin has no significant effect in reducing pain intensity. the use of gabapentin as a premedication for limbs orthopedic surgery under general anesthesia reduce pain and the need for durgs in recommended.
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| Descriptor
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1. Pain, Postoperative.- Descriptors: Pain, Postoperative
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gabapentin
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Acetaminophen
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Orthopedics
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Extremities
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| Added Entry
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Kashefi, Parviz, Supervisor
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| Translated Title Supplied by Cataloguer
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بررسی پره امپتیومولتی مدال ترکیب گاباپنتین و استامینوفن خوراکی بر درد بعد از عمل ارتوپدی اندام تحتانی و مقایسه آن با گروه شاهد
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