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" Evaluation of three different strategies (intravenous hydroxyl ethyl starch, intravenous albumin 20 percent, and oral cabergoline) for prevention of ovarian hyperstimulation syndrome in patients undergoing ovulation induction "
/ندا مقاره عابد
; Ataollah Ghahiri, Minoo Movahedi
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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103527
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| Doc. No
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T15140
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WP,540,M696e,2014
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| Main Entry
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Moghareh Abed, Neda
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| Title & Author
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Evaluation of three different strategies (intravenous hydroxyl ethyl starch, intravenous albumin 20 percent, and oral cabergoline) for prevention of ovarian hyperstimulation syndrome in patients undergoing ovulation induction/ندا مقاره عابد
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| College
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Schools, Medical
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| Date
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, 2014
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| Degree
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Obstetric and Gynecolgy, Specialty
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9 p.: tab.
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| Note
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This thesis is a research project with project ID: 392298
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| Abstract
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the purpose of this study was to compare three different strategies, IV hydroxyethystarch (HES), IV human albumin (HA), and oral cabergoline (Cb) in the prevention of ovarian hyperstimulation syndrome (OHSS). in this prospective randomized clinical trial, 91 women at high risk of developing OHSS were allocated in three groups, group one received 2 vial (2*50ml) IV human albumins, in group two 1000ml of 6 percent HES was administered IV, both groups 30 minutes after oocyte retrieval within 4 hours. group three, 31 infertile patients received oral cabergoline 0.5 mg daily for 7 days after oocyte retrieval. patients were visited 14+/-1 days after IVF and if betaHCG level>10, transvaginal ultrasonography was performed two weeks later to confirm intrauterine pregnancy. patients were followed up weekly for 3 months for signs of OHSS and were also informed about the signs of OHSS and asked to contcat immediately if any symptoms of were detected. none of the participants in group HES developed severe OHSS and only 3 patients (10 percent) developed mild to moderate OHSS. the incident of severe OHSS was significantly higher in albumin group compared to cabergoline and HES group (p=0.033 and p<0.001 respectively). also the probability of developing severe OHSS was higher in cabergoline group than group HES (p=0.031). the findings from this study suggest that administration of 1000 ml of hydroxyethylestarch 6 percent has a higher prophylactic effect compared to administration of IV human albumin and oral cabergoline.
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| Descriptor
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1. Ovarian Hyperstimulation Syndrome.- Descriptors: Ovarian Hyperstimulation Syndrome
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cabergoline
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Ovarian Diseases
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Ovulation
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Ovulation Induction
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| Added Entry
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Ghahiri, Ataollah, Supervisor
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Movahedi, Minoo, Supervisor
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| Translated Title Supplied by Cataloguer
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بررسی کارایی ۳ استراتژی مختلف از تزریق داخل وریدی هیدروکسی اتیل استارچ آلبومین ۲۰ درصد وریدی و کابرگولین خوراکی جهت پیشگیری از سندرم تحریک بیش از حد تخمدان در بیماران تحت القای تخمک گذاری
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