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" Relationship between obstructive sleep apnoea [ right: Apnea ] and 30-day mortality among patients with pulmonary embolism (according to STOP-Bang Questionnaire) "
/Amin Ahmadpour
; Farzin Ghiyasi
; Babak Amra
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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105918
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| Doc. No
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T16417
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| Call number
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WG420,A286r,2015
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| Main Entry
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Ahmadpour, Amin
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| Title & Author
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Relationship between obstructive sleep apnoea [ right: Apnea ] and 30-day mortality among patients with pulmonary embolism (according to STOP-Bang Questionnaire)/Amin Ahmadpour
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| College
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Schools, Medical
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| Date
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, 2015
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| Degree
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Internal Medicine, Speciality
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| Page No
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18 p.: tab
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| Note
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This thesis is a research project with project ID: 393245
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امین احمدپور
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| Abstract
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Introduction: pulmonary embolism (PE) is the most life-threatening form of venous thrombosis which causes the majority of mortalities in this category. Obstructive sleep apnea (OSA) has been indicated as one of the risk factors for thromboembolism because of haemostatic alterations. The present study was designed to seek for relationship between OSA and 30-day mortality of patients PE. Method and material: This prospective cohort study was conducted among 137 consecutive patients referred to Al-Zahra hospital with symptoms of pulmonary embolism and preliminary stable hemodynamic. Confirmation of PE was made by multislice CT pulmonary angiography and in the case of contraindication, V/Q lung scan and doppler sonography were done. A Stop-Bang Questionnaire was used to determine patients with high and low risk of OSA. Patients were followed up for one month and their survivals were recorded.Results: This study showed that there was no relationship between OSA and 30-day mortality (p-value= 0.389, odd ratio (OR) = 1.582). However history of chronic kidney disease was diagnosed as a risk factor for 30-day mortality among PE patients (p-value= 0.029, odd ratio= 4.93). In addition to chronic kidney disease, results of univariate analysis revealed that hypertension (p-value=0.003), main thrombus (p-value= 0.004) and segmental thrombus (p-value= 0.022) were associated with 30-day mortality. Conclusion: Results of this study showed 30-day mortality was not affected by OSA directly. In fact, it was affected by complications of OSA such as hypertension and thrombus. Also positive history of chronic kidney disease increased risk of 30-day mortality.
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| Descriptor
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Pulmonary Embolism
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Venous Thromboembolism
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Sleep Apnea Syndromes
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Cause of Death
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Surveys and Questionnaires
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| Added Entry
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Ghiyasi, Farzin Thesis advisor
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Amra, Babak Consulting advisor
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| Translated Title Supplied by Cataloguer
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بررسی ارتباط آپنه انسدادی خواب و مرگ 30 روزه بیماران مبتلا به آمبولی ریه با همودینامیک اولیه پایدار ( براساس پرسشنامه stopbang
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