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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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105920
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| Doc. No
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T16420
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| Call number
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WO200,K13k,2015
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| Main Entry
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Kajbaf, Abdollah
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| Title & Author
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Ketamine administration makes patients and physicians satisfied during gastro-enteric endoscopies\ Abdollah Kajbaf
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| College
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Schools, Medical
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| Date
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, 2015
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| Degree
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Emergency Medicine, Speciality
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| Page No
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15p.: diag, tab
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| Note
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This is a research dissertation with project ID:393448
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عبداله کجباف
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| Abstract
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Background: A suitable sedative status during gastro-enteric endoscopies results in better physicians' approach and more stable view of internal organs. There are several medications used for induction of sedation such as midazolam, opioids and propofol but as we searched there is no study to evaluate effect of ketamine for sedation in endoscopic procedures of adult patients.Methods and materials: Patients who were candidates for gastro-enteric endoscopy during years 2014-2015 were included into the study and divided into two groups of case (administered 5 mg/kg of oral ketamine half an hour before initiation of the procedure) and control (administered placebo in a same pattern). After finishing endoscopy, patients and physicians' satisfaction of sedation were assessed and SPSS-22 used for data analysis.Results: eighty-six patients participated into the study of which 43 were in each groups of case and control. There were no difference between groups regarding age (P=0.11), sex (P=0.07) and level of academic degree (P-value=0.33). The pain and discomfort score were 2.4±1.8 and 5.81±1.48 in case and control groups respectively which showed significant differences between groups (P-value‹0.001). Mann-Whitney test revealed statistical difference between groups about physician's satisfaction of sedation during endoscopy (P-value‹0.001).The sedation score were assessed in both groups and patients who received ketamine had better sedative status (Mann-Whitney test; P-value‹0.001). None of the patients in case group were completely awake but all of patients in control group were awake. The number of retching during endoscopy showed that individuals in control group had more frequent retching episodes (P-value=0.04).Conclusion: our data showed that a low-dose oral administration of ketamine could make a suitable sedation for gastro enteric endoscopy. Patients experienced less pain and less frequent retching and physicians had greater satisfaction of sedation compared with those placebo treated group. We would like to suggest using ketamine as a suitable medication for induction of sedation during gastro endoscopic procedures if there is no contraindication.
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| Descriptor
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Conscious Sedation
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Ketamine
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Pain Management
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Gastroenteritis
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Analgesics
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Endoscopy, Gastrointestinal
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Emergency Medicine
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| Added Entry
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Majidinejad, Saeed, Thesis advisor
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Adibi, Peyman, Thesis advisor
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| Translated Title Supplied by Cataloguer
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بررسی تاثیر دوز پایین کتامین خوراکی در کاهش درد در بیماران و راحتی پزشکان حین انجام آندوسکوپی یک مطالعه بالینی شاهددار
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http://elib.mui.ac.ir/site/catalogue/105920
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