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" The prevalence of high risk human papillomavirus in ovarian endometriosis "
/ Maryam Derakhshan
; Mitra Hidarpour, Majid Khirollahi
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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106132
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| Doc. No
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T16447
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| Call number
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WP390,D427p,2015
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| Main Entry
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Derakhshan, Maryam
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| Title & Author
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The prevalence of high risk human papillomavirus in ovarian endometriosis/ Maryam Derakhshan
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| College
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Schools, Medical
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| Date
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, 2015
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| Degree
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Pathology, Speciality
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| Page No
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14p.: tab
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| Note
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This is a research dissertation with project ID: 391374
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مریم درخشان
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| Abstract
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In this study, we aimed to determine the prevalence of human papillomavirus (HPV) in ovarian endometriosis and ovarian tissue from women without endometriosis. Understanding the pathogenesis of the disease could help us design preventative strategies as well as novel and appropriate treatment approaches in this regard. In this cross-sectional study, formalin fixed and paraffin embedded tissues of 50 ovarian endometriosis and 49 ovaries without endometriosis were evaluated for the presence of high risk HPV using polymerase chain reaction (PCR) technique. Prevalence of HPV infection and other related characteristics of studied population were compared.High riskHPV infection was detected in 42(84%) and 27(55.1%) of samples with and without endometriosis, respectively (P=0.02, X2= 8.32). Mean of age and parity was not significantly different in subjects with and without HPV infection in both studied groups (P=0.7 and P=0.06 for age in case and control groups, respectively and P=0.32 and P=0.09 for parity in case and control groups, respectively).The results of our study indicated a higher rate of high risk HPV infection among patients with endometriosis. The findings could provide us baseline information for future studies regarding the pathogenesis of endometriosis and the role of viral infection and their impact on future cancer development in this group of patients
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| Descriptor
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Endometriosis
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Papillomaviridae
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Papillomavirus Infections
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Risk Factors
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Ovarian Diseases
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Pathology
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| Added Entry
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Heidarpour, Mitra, Thesis advisor
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Khirollahi, Majid, Thesis advisor
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| Translated Title Supplied by Cataloguer
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بررسی توزیع فراوانی ویروس پاپیلومای انسانی در بیماران آندومتریوز در مقایسه با افراد نرمال
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