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" Investigation of changes in Brain natriuretic Peptide serum levels and its diagnostic value in patients with minor and moderate head trauma, in patients referred to emergency department of Alzahra hospital, Isfahan, 2013-2014 "


center : Isfahan University of Medical Sciences
Document Type : Latin Dissertation
Language of Document : English
Record Number : 106214
Doc. No : T16465
Call number : WL354,K42i,2015
Main Entry : Keshavarz, Eshagh
Title & Author : Investigation of changes in Brain natriuretic Peptide serum levels and its diagnostic value in patients with minor and moderate head trauma, in patients referred to emergency department of Alzahra hospital, Isfahan, 2013-2014\ Eshagh Keshavarz
College : Schools, Medical
Date : , 2015
Degree : Speciality
field of study : Emergency Medicine
Page No : 21p.: diag, tab
Note : This is a research dissertation with project ID:392599
: اسحاق کشاورز
Abstract : Background: Head trauma is one of the most common reasons for emergency department (ED) care. Over the past decade, initial management strategies in mild and moderate head trauma have become focused on selective CT use based upon presence or absence of specific aspects of patient history and/or clinical examination. This selective management has received more attention following reports of increased cancer risk from CT scans. In recent years, changes in serum BNP levels following head trauma have been investigated by some researchers. We investigated the changes in serum levels of BNP in patients with mild and moderate head trauma, in whom the first brain CT scanning was normal.Method: This study is a cross-sectional, descriptive research. It was performed in patients with mild and moderate head trauma. 41 patients with isolated mild and moderate traumatic brain injury (TBI) (GCS=9-15) were included. First brain CT scans were obtained during 2 hours after ED arrival and second one after 24 hours. Plasma BNP levels were determined using a specific immunoassay system.Result: 23 patients were in group A (with normal first and second brain CT) and 18 patients in group B (with normal first and abnormal second brain CT). With P-Value= 0.001, serum BNP level=9.04 was determined for differentiating two groups. Conclusion: We concluded that serum BNP level is higher in patients with mild and moderate head trauma with delayed pathologic changes in second brain CT relative to patients with mild and moderate head trauma and with normal delayed brain CT.
Descriptor : Craniocerebral Trauma
: Natriuretic Peptide, Brain
: Cone-Beam Computed Tomography
: Brain Injuries
: Emergency Medicine
Added Entry : Thesis advisor Azizkhani, Reza,
Translated Title Supplied by Cataloguer : بررسی تغییرات و ارزش تشخیصی ماده بی ان پی در سرم بیماران با ترومای سر از نوع خفیف و متوسط در بیماران مراجعه کننده به اورژانس بیمارستان الزهرا در سالهای ۱۳۹۲-۱۳۹۳
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