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" Etiology and outcome in patients with upper gastrointestinal bleeding: A population-based study on 4747 patients in the central region of Iran "
\ Shervin Badihian
; Mohammad Minakari
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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English
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| Record Number
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107380
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| Doc. No
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T16664
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WI143,B136e,2016
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| Main Entry
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Badihian, Shervin,
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| Title & Author
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Etiology and outcome in patients with upper gastrointestinal bleeding: A population-based study on 4747 patients in the central region of Iran\ Shervin Badihian
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| College
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Schools, Medical
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| Date
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, 2016
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| Degree
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M.D
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| field of study
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Medicine
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| Page No
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26p.: tab
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| Note
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This is a research dissertation with project ID: 293027
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شروین بدیهیان
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| Abstract
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Objective: To investigate etiology and outcome in patients with upper gastrointestinal bleeding (UGIB).Methods: Medical records of 5499 patients diagnosed with GIB and admitted to Alzahra referral hospital in central region of Iran were retrospectively reviewed for demographic data, comorbidities, history of smoking, History of taking NSAIDs, presenting symptoms, endoscopic findings, therapeutic endoscopy, blood and blood products’ infusion, surgical intervention and mortality.Results: After initial review a total of 4747 patients were enrolled in the study, of those 69.2% were male, with mean age of 55.46 ± 21.98 years. Hematemesis was the most frequent presenting symptom (63.5%). Peptic ulcer (duodenal ulcer in most cases) was seen to be the main reason for UGIB (42.4%). Rebleeding (present in 16.5% of patients), was found to be more frequent in patients with: higher age, presenting sign of hematochezia and hypotension, history of taking NSAIDs and smoking, history of other comorbid diseases, history of bleeding of due to UGI tract neoplasm and esophageal varices, history of needing blood or blood products’ infusion, and history of therapeutic endoscopy or surgical intervention (P-value <0.005). We found that mortality (5.5% in total) was also higher in the same group of patients that were seen to have a higher tendency for rebleeding (P-value<0.005). Conclusion: History of smoking and talking NSAIDs, gastric and esophageal malignancies, and longer hospital stay may be important predisposing factors for rebleeding and mortality in patients with UGIB.
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| Descriptor
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Gastrointestinal Hemorrhage
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Patient Outcome Assessment
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Smoking
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| Added Entry
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Minakari , Mohammad, Thesis advisor
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| Translated Title Supplied by Cataloguer
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علل و نتیجه در بیماران مبتلا به خونریزی گوارشی: مطالعه مبتنی بر جمعیت در 4747 بیمار در منطقه مرکزی ایران
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