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" Long-term cardiovascular outcomes associated with early repolarization on electrocardiography; a 10-year population-based, longitudinal study "
\ Vahid Sharif Arani
; Mohammadreza Samieinasab, Masoomeh Sadeghi
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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107699
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| Doc. No
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T17129
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WG140,S531l,2016
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| Main Entry
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Sharif Arani, Vahid
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| Title & Author
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Long-term cardiovascular outcomes associated with early repolarization on electrocardiography; a 10-year population-based, longitudinal study\ Vahid Sharif Arani
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| College
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Schools, Medical
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| Date
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, 2016
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| Degree
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Speciality
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| field of study
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cardiology
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17p.
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| Note
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This is a research dissertation with project ID: 393317
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وحید شریف آرانی
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| Abstract
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Introduction: The clinical importance of early repolarization (ER) pattern in the electrocardiogram of cardiovascular disease free individuals is unclear. We investigated the association of ER with long-term cardiovascular events and mortality in Iranian general population.Methods: Subjects were selected from the Isfahan Cohort Study, a population-based, 10-year longitudinal study conducted in central Iran from 2001 to 2011. Subjects’ demographic and medical data were retrieved and 12-lead electrocardiograms were retrospectively analyzed for the presence of ER. Study outcomes included cardiovascular events (unstable angina, myocardial infarction, stroke, and sudden cardiac death) and cardiovascular and all-cause mortality. Results: A total of 3035 subjects (51% female) with mean age of 50.5 years (SD = 11.4) were studied. Early repolarization was present in 225 (7.4%) subjects with higher frequency in men than in women (13.6 vs. 1.4%, P <0.001). Follow-up data of 2695 subjects were available. Cardiovascular events and cardiovascular and all-cause mortality occurred in 401 (14.8), 79 (2.9), and 189 (7.0) subjects, respectively. After controlling for traditional cardiovascular risk factors, an association was found between ER and cardiovascular (adjusted hazard ratio [95% CI] = 5.681 [2.173-14.925]) and all-cause mortality (adjusted hazard ratio = 2.652 [1.170-6.024]) in women. No significant association was found between ER and study outcomes in men.Conclusions: In Iran, ER is common in the general population of men, but has no obvious long-term cardiovascular risk. In women, ER is relatively rare but may be associated with long-term cardiovascular risk. Further studies with larger sample size are still required in this regard
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| Descriptor
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Echocardiography
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Cardiovascular Diseases
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Arrhythmias, Cardiac
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Myocardial Infarction
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Samieinasab, Mohammadreza, Thesis advisor
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Sadeghi, Masoomeh, Thesis advisor
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| Translated Title Supplied by Cataloguer
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نتایج بلند مدت قلبی عروقی مرتبط با رپلاریزاسیون در اوایل نوار؛ مبتنی بر جمعیت، مطالعه طولی 10 ساله
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