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center
:
Isfahan University of Medical Sciences
Document Type
:
Latin Dissertation
Language of Document
:
English
Record Number
:
107798
Doc. No
:
T17145
Call number
:
WJ378,S163e,2016
Main Entry
:
Salehi Najafabadi, Yaser
Title & Author
:
The effect of omega-3 supplementation on serum inflammatory factors in hemodialysis patients\ Yaser Salehi Najafabadi
College
:
Schools, Medical
Date
:
, 2016
Degree
:
Speciality
field of study
:
Internal Medicine
Page No
:
16P.: tab
Note
:
This is a research dissertation with project ID: 293185
:
یاسر صالحی نجف آبادی
Abstract
:
Background : the level of inflmatory factors such as tumor necrosis factor-alfa (TNF-α) and C-reactive protein (CRP) are increased in ESRD patients and And has been associated with increased mortality in these patients. Omega-3 is known as a regulator of inflammatory system. The aim of this study is evaluation of effect of omega-3 supplementation on TNF-α and CRP level in ESRD patients. Method :in This randomized controlled double-blind clinical trial,54 ESRD patients in tow hemodialysis centers of Isfahan university hospitals was evaluated. TNF-α and high specific-CRP (hs-CRP) was measured.In the experimental group ,Patients were treated with Omega-3 capsules (1 gram capsules- Making factory Zahravi- containing Eicosapentanoic 180mg and Dosahexanoic 120mg) three capsules per day ( 3g/day ) and the control group received placebo capsules were manufactured by the Zahravi with the same shape and size for 6 consecutive months.Results :There were no differences in CRP and TNF-α leveles in the start and the end of study between two groups (P > 0.05) . Conclusion : we conclude that the use of 3g of omega-3 per day for 6 consecutive months caused no significant effect on serum levels of TNF-α and CRP in the heamodialysis population.Further studies with larger numbers of patients and longer duration of treatment are recommended.
Descriptor
:
Renal Dialysis
:
Fatty Acids, Omega-3
:
Dietary Supplements
:
Inflammation
Added Entry
:
Mortazavi, Mojgan, Thesis advisor
Translated Title Supplied by Cataloguer
:
بررسی تاثیر مکمل امگا 3 بر روی فاکتورهای التهابی در بیماران همودیالیز
http://elib.mui.ac.ir/site/catalogue/107798
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The effect of omega-3 supplementation on serum inflammato...
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