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center : Isfahan University of Medical Sciences
Document Type : Latin Dissertation
Language of Document : English
Record Number : 107845
Doc. No : T17154
Call number : WO350,R147c,2016
Main Entry : Rahimianfar, Aliakbar
Title & Author : Comparative evaluation between two methods of induced hypotension with infusion of remifentanil and labetalol during sinus endoscopy in AL Zahra and Kashani Medical Centers\ Aliakbar Rahimianfar
College : Schools, Medical
Date : , 2016
Degree : Speciality
field of study : Anesthesiology
Page No : 8p.: diag, tab
Note : This is a research dissertation with project ID: 394735
: علی اکبر رحیمیان فر
Abstract : Objective: This study aimed to compare two methods of controlled hypotension usinglabetalol and remifentanil in terms of capability to create controlled hypotension andto investigate the obtained complications, and satisfaction rate of surgeon and patientduring functional endoscopic sinus surgery.Methods: In this prospective clinical trial, 62 patients underwent endoscopic sinussurgery in Al‑Zahra and Ayatollah Kashani Hospitals of Isfahan were divided into twogroups: in the first group, 20 mg bolus dose of labetalol and then infusion of it, at arate of 0.5–2.0 mg/min and in the second group, remifentanil with dose of 0.5–1 μg/kgstarted and then 0.25–0.5 μg/kg/min were prescribed. Hemodynamic parametersduring anesthesia and recovery time, surgeon and patient satisfaction, and recoverytime were measured and recorded.Findings: Hemodynamics variable were comparable between two groups at differenttimes of the study. The mean of bleeding and the frequency of side effects werehigher in labetalol group (P = 0.033 and P < 0.0001, respectively). The median ofsurgeon satisfaction score in remifentanil group was statistically higher in labetalolgroup (P < 0.0001). Recovery time, fluid requirement, and pain score in labetalol groupreported significantly more than remifentanil group. Richmond Agitation–Sedation Scalestatus at time points in the postanesthetic care unit showed differences between groups.Conclusion: Both labetalol and remifentanil could produce effective induce controlledhypotension in patients with infusion after a bolus doses. Remifentanil is a short‑actingnarcotic drug; then, patient satisfaction was better and recovery time was shorter. Fromthe economic aspect, labetalol prefers to remifentanil
Descriptor : Hypotension, Controlled
: Labetalol
: Anesthetics, Intravenous
: Endoscopy
: Anesthesia, General
Added Entry : Sajedi, Parvin, Thesis advisor
: Khalili, Gholamreza, Thesis advisor
Translated Title Supplied by Cataloguer : بررسی مقایسه ای دو روش هیپوتانسیون کنترله با لابتالول و رمی فنتانیل در بیماران آندوسکوپی سینوس بینی در بیمارستان الزهرا و کاشانی در طی سالهای 95-94
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