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" Effect of Nebulized Budesonide and Intravenous Dexamethasone on Tracheal Tube Cuff Leak in Intubated Patients Admitted to Intensive Care Unit "
\ Abbas Emami nejad
; Saeed Abbasi
; Parviz Kashefi, Babak Ali Kiaei
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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109866
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| Doc. No
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T17355
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| Call number
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WO280,E53e,2016
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| Main Entry
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Emami Nejad, Abbas
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| Title & Author
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Effect of Nebulized Budesonide and Intravenous Dexamethasone on Tracheal Tube Cuff Leak in Intubated Patients Admitted to Intensive Care Unit \ Abbas Emami nejad
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| College
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Schools, Medical
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| Date
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, 2016
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| Degree
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Speciality
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| field of study
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Anesthesiology
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| Page No
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15 P.: tab
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| Note
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This is a research dissertation with project ID: 395291
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عباس امامی نژاد
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| Abstract
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Introduction: Tracheal intubation is a common action in intensive care unit, but it may cause laryngeal edema or laryngotracheal injury which leads to edema. Cuff-leak test is done in order to define the upper airway patency. Considering this point that laryngeal edema would be treated by anti-inflammatory agents, our aim was to evaluate the impact of nebulized budesonide on ICU patients’ relief and comparison of nebulized budesonide efficacy with dexamethasone. Materials and Methods: In our clinical trial, 270 intubated patients from ICU was randomly selected and divided into threegroups (each group was included 90 persons): intravenous dexamethasone, nebulized budesonide, and controls. All the patients were monitored in 0, 12, 24, 36, and 48 h of starting follow up. Hemodynamic parameters and cuff-leak ratio were measured and data was analyzed by SPSS (ver. 20).Results: Our findings revealed that dexamethasone and budesonide treatment approaches was beneficial for increasing of cuff-leak volume (p<0.001). Furthermore, superiority of mentioned methods was significantly found (p<0.001). Moreover, hemodynamic parameters were not altered and it was in normal range in both dexamethasone and budesonide groups (p>0.05).Conclusion: Our findings demonstrated that use of budesonide and dexamethasone is beneficial in intubated ICU patients and these approaches can reduce the tracheal intubation complications. Also, , budesonide could be a trustworthy substitute treatment strategy instead of intravenous dexamethasone
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| Descriptor
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Intubation, Intratracheal
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Laryngeal Edema
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Nebulizers and Vaporizers
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Desoximetasone
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| Added Entry
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Abbasi, Saeed, Thesis advisor
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Kashefi, Parviz, Consulting advisor
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Ali Kiaei, Babak Consulting advisor
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| Translated Title Supplied by Cataloguer
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بررسی تاثیر nebulized bude sonid و دگزامتازون وریدی بر روی لیک کاف لوله تراشه در بیماران اینتوبه بستری در بخش مراقبت های ویژه الزهرا (س )
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