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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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110297
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| Doc. No
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T18225
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WP320,J23o,2017
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| Main Entry
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Jafari fesharaki, Sajedeh
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| Title & Author
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Omega 3 supplementation effects on poly cystic ovary syndrome symptoms and metabolic syndrome \ Sajedeh Jafari fesharaki
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| College
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Schools, Medical
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| Date
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, 2017
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| Degree
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Speciality
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| field of study
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Gynecology
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| Page No
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18 P.: tab
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| Note
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This is a research dissertation with project ID: 394057
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ساجده جعفری فشارکی
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| Abstract
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Introduction: Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder with unknown etiology and with different complications. The aim of this study was to evaluate the effect of Omega 3 supplementation on PCOs symptoms and metabolic syndrome.Methods and materials: This double-blind clinical trial was performed in 2015 in Alzahra and Shahid Beheshti hospitals, Isfahan, Iran, on 88 patients with PCOs. Intervention group took omega 3 supplements with dose of 2 gr per day for six months (two capsules), but control group received 2 olive oil capsules. Finally, ultrasound and lab findings and the recovery rate of menstrual disorders in both groups was compared.Results: After 6 months’ intervention, waist circumference (WC) was significantly lower in omega 3 as compared to control (81.18 ± 2.87 vs. 84.22 ± 2.61 cm, respectively, P-value <0.0001). HDL was increased (47.2 ± 1.37 vs. 41.56 ± 1.34 mg/dl, respectively, P-value<0.0001), while LDL (107.79 ± 1.68 vs. 117.4 ± 1.57 mg/dl, respectively), triglyceride (116.02 ± 3.13 vs. 125.06 ± 2.91 mg/dl, respectively) and cholesterol (180.34 ± 6.34 vs. 189.56 ± 5.93 mg/dl, respectively) in omega 3 were significantly lower than control (P-values<0.0001). The regularity of periods in omega 3 was significantly shorter than control (29.83 ± 4.68 vs. 47.11 ± 8.72 days, respectively, P-value<0.001). Conclusion: Omega 3 improves lipid profiles decrease, WC and interval between periods, while weight, Hip C, FBS, number of ovarian follicle, size of ovary, bleeding volume, menstrual bleeding and hirsutism score did not change by administration of omega 3.
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| Descriptor
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Polycystic Ovary Syndrome
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Fatty Acids, Omega-3
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Metabolic Syndrome X
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Dietary Supplements
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| Added Entry
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Khani, Behnaz , Thesis advisor
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Mardanian, Farahnaz Thesis advisor
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| Translated Title Supplied by Cataloguer
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تاثیر مکمل امگا 3 بر روی علایم سندروم PCO و متابولیک براساس هزینه
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http://elib.mui.ac.ir/site/catalogue/110297
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