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" Factors associated with adherence to treatment in Iranian patients with inflammatory bowel disease "
\ Zohre Forouzan
; Mohammad hasan Emami
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Isfahan University of Medical Sciences
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Document Type
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Latin Dissertation
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Language of Document
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English
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Record Number
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111171
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Doc. No
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T18335
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Call number
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WI420,F727f,2017
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Main Entry
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Forouzan, Zohre
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Title & Author
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Factors associated with adherence to treatment in Iranian patients with inflammatory bowel disease\ Zohre Forouzan
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College
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Schools, Medical
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Date
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, 2017
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Degree
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MD
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field of study
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Medicine
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Page No
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No paging.: tab
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Note
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This is a research dissertation with project ID: 291081
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زهره فروزان
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Abstract
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Background: In this study, we investigated several socioeconomic, clinical and psychological factors associated with medication adherence in a sample of Iranian patients with inflammatory bowel disease (IBD).Methods: This study was conducted on 110 IBD patients from 2013-2014 in Isfahan, Iran. The patients were invited to complete three anonymous questioners including the Hospital and Anxiety Depression Scale (HADS) for assessing the levels of anxiety and depression; Inflammatory Bowel Disease Questionnaire (IBDQ-9) for the quality of life; and a visual analogue scale assessing the medication adherence. A self-assessment adherence rate of more than 80% was considered "appropriate adherence".Results: Overall, 99 patients completed the questionnaires. Among them,77.8% reportedly adhered to their medications. There was no statistical difference between adherence and non-adherence rates in terms of gender, educational status, disease type, disease severity, and family history of IBD. Conversely, single patients (100% vs. 74.1%; p=0.03), non-smokers (79.4% vs. 0.0%; p= 0.04), patients receiving immunosuppressive drugs (100% vs. 71.9%; p=0.01) and corticosteroids (95.1% vs. 65.5%; p=0.01) were more likely to be adhered than their counterparts. No differences emerged in terms of the mean HADS scores in either of the sexes. The mean IBDQ-9 score was significantly higher in adhered patients only in females (31.08 ±11.6 vs. 24.7±9.1; p=0.04), but not in males.Conclusion: The adherence rate in Iran is almost similar to developed countries. Single marital status, not smoking, receiving corticosteroids and immunosuppressive drugs and higher IBDQ-9 score in females are associated with higher adherence rate in Iranian patients
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Descriptor
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Inflammatory Bowel Diseases
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Medication Adherence
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Treatment Refusal
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Patient Compliance
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Added Entry
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Emami, Mohammad hasan , Thesis advisor
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