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" Decoy Cell Viruria in Kidney Transplant Patients. Does it correlate with Renal Function? "
/ Akram Abedi
; Azar Baradaran
; Mojgan Mortazavi
center
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Isfahan University of Medical Sciences
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Document Type
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Latin Dissertation
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Language of Document
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English
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Record Number
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111279
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Doc. No
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T18343
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Call number
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QW165.5,.P2,A138d,2017
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Main Entry
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Abedi , Akram
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Title & Author
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Decoy Cell Viruria in Kidney Transplant Patients. Does it correlate with Renal Function?/ Akram Abedi
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College
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Schools, Medical
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Date
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, 2017
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Degree
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Speciality
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field of study
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Pathology
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Page No
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12 p.: tab.
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Note
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This thesis is a research project with project ID: 393367
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Abstract
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Objective: BK virus (BKV) infection after kidneytransplantation has been a topic of great interest inthe recent decade. Prospective screening studieshave revealed that BKVN is principally an early complicationof renal transplantation occurring within thefirst post-transplant year in most cases. The aim ofthe present study was to observe the incidence ofdecoy cell viruria in renal transplant recipients. Furthermore,correlation of decoy cell viruria with graftfunction was assessed.Methods: This analytic cross-sectional study wasconducted in the Transplant Center of Alzahra Hospital,Isfahan, Iran between Jun 2014 and June2015. Clinical screening for polyomavirus infectionwas done by means of urine cytological evaluationfor decoy cells. Urine samples were analyzed inthree steps including 2-4 months after transplantation,three and six months later Results: Thirty-three patients (22 male and 11 female)received kidney transplant from living donors.The average of patients’ age was 41.9±12.83(range: 20-63 years). Peritoneal and hemodialysis were used for 15.6% and 84.4% of recipients. Theoccurrence of decoy cell viruria at the time of enrollment,3 and 6 months later was found in 18.2%,10.7% and zero, respectively.Conclusion: As urine cytology is easy to performand of low cost, it is a useful tool for the investigationof active polyoma virus infection. Moreover, thefindings advocate that the presence of decoy cellsalong with high creatinine is a better indicator of thevirus presence
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Descriptor
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BK Virus
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Kidney Transplantation
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Polyomavirus Infections
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Added Entry
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Baradaran , Azar , Thesis advisor
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Mortazavi, Mojgan , Consulting advisor
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