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" A 6-year Survey of the Spectrum of Renal Disorders on Native Renal Biopsy Results in Central Iran, and a Review of Literature "
\ Erfan Behzadi
; Diana Taheri
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Isfahan University of Medical Sciences
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| Document Type
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Latin Dissertation
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English
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| Record Number
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114055
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| Doc. No
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T19044
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| Main Entry
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Behzadi, Erfan
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| Title & Author
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A 6-year Survey of the Spectrum of Renal Disorders on Native Renal Biopsy Results in Central Iran, and a Review of Literature\ Erfan Behzadi
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| College
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Schools, Medical
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| Date
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, 2018
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| Degree
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MD
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| field of study
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, Medicine
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| Page No
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26 p: tab
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| Note
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This is a research dissertation with project ID: 293241
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عرفان بهزادی
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Electronical
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| Abstract
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Introduction: Native renal biopsy reports in previous studies that are mostly originated in western countries, show various results in different parts of the world. In this study we aimed to determine the prevalence of renal biopsy disorders in Iran and compare it with other studies in the world.Methods: This cross sectional study evaluated consecutive native renal biopsies performed in four centers in Isfahan, Iran from2009to2014. We also reviewed other relevant studies in Iran and the world.Results: Overall, 1547 renal biopsies were reviewed.493cases were excluded (transplant or re-biopsy cases), having a total of 1054 cases (43.3%female) included in our study with a mean (±SD) age of 33.1 (±18.5) years. The first three most prevalent diagnoses were focal segmental glomerulosclerosis (FSGS) (24.8%), minimal change disease (MCD)(14.2%), and membranous glomerulonephritis (MGN)(9.6%). IgA nephropathy (IgAN) was more prevalent among men, whereas lupus nephritis had a higher prevalence in women. In three out of six previous studies conducted in Iran, the most prevalent pathological diagnosis was MGN, in two others MCD predominates, and in the other study FSGS had the highest prevalence. In Europe and Western Pacific Region, IgAN was by far the most prevalent glomerulonephritis, while studies in other parts of the world show conflicting results. Conclusions: The most prevalent diagnosis in our study was FSGS, which compared to previous studies in Iran, seems to have an increasing prevalence. It has been realized that having a national registry is crucial to determine current status, better planning and management of renal disorders.
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| Added Entry
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Taheri, Diana , Thesis advisor
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