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language of document : English
Material Type : طرح تحقیقاتی/ پروژه لاتین
Record number : 51463
doc. No : R2999
main entry : Ashtari, Fereshteh
title & author : Specific IgE against wheat, soy and nuts in patients with Multiple Sclerosis [Research Project]/Executer: Fereshteh Ashtari, Fatemeh Jamshidi; ETC: Raheleh Shokouhi Shoormasti, Zahra Pourpak, Fariborz Zandieh, Leila Azadbakht
Publication statement : Isfahan: Isfahan University of Medical Sciences, Vice Chancellery for Research , 2013.
Physical Description : (no pagination):tab
Notes : عنوان به فارسی : بررسی توزیع فراوانی آنتی بادی‭ IgE‬اختصاصی نسبت به آلرژن های شایع غذایی در بیماران مبتلا به مولتیپل اسکلروز در مقایسه با گروه شاهد
Notes : To evaluate the specific IgE antibody level against wheat, soy and nuts as a part of major food allergens among patients with Multiple Sclerosis (MS) compared to healthy control group. The present case-control study was conducted among patients with MS disease who were referring to Kashani MS clinic in Isfahan, Iran during Nov 2011 to Nov 2012. Case group consist of 48 MS patients and control group included of 48 healthy individual who were matched with the case group regarding age and sex variables. ImunoCAP system technique was used to determine specific IgE antibody against wheat, soy and nuts in serum of all subjects. In both groups 11 patients ( 22 percent ) were male and 37 patients ( 78 percent ) were female with mean age of 30.8+- 6.6 years in MS patients and 30.9 + - 6.3 years in control group. As a whole specific IgE antibody against wheat, soy and nuts were positive in 10.4 percent, 6.2 percent and 9.4 percent of total study subjects, respectively. In different groups specific IgE antibody against wheat was positive in 3 MS patients and 7 healthy individuals in control group (P-value=0.18). Specific IgE antibody against soy was positive in 6 subjects in control group and none of MS patients (P-value=0.01). Specific IgE antibody against nuts was positive in 2 MS patients and 7 controls (P-value=0.08). specific IgE against wheat, soy and nuts, in MS patients were not more than controls; moreover IgE against soy was significantly higher in control group. Food allergens may be very unlikely to affect MS development. However, further prospective studies with larger sample size are needed to confirm this finding.
Notes : Print
descriptor : Multiple Sclerosis
: Autoimmune Diseases
: Immunoglobulin E
: Food Hypersensitivity
: Soy Foods
Originating Source : IRIsfahan University of Medical Sciences
publication type : p
Source : Vice Chancellery for Research
Ended Date : 2013
Project code : 189035
 
 
 
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