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language of document : English
Material Type : طرح تحقیقاتی/ پروژه لاتین
Record number : 51482
doc. No : R3041
main entry : Kelishadi, Roya
title & author : Familial aggregation of the components of metabolic syndrome [Research Project]/Executer: Roya Kelishadi; ETC: Soror Arman, Mohammad Hasan Modab, Mohsen Hosseini, Hossein Saneian, Mohammad Reza Sabri, Mahin Hashemipour
Publication statement : Isfahan: Isfahan University of Medical Sciences, Vice Chancellery for Research, 2012.
Physical Description : [No paging] .:tab
Notes : عنوان به فارسی : مطالعه خانواده محور پیشگیری از بیماری های قلبی عروقی و سندرم متابولیک
Notes : To investigate cardiometabolic factors in children of parents with metabolic syndrome (MetS), and to determine the association of these factors among children and their parents. This cross-sectional study was conducted as part of the baseline survey of a longitudinal study. According to inclusion/exclusion criteria, 800 children of parents with diagnosed MetS were selected by convenience sampling. Cardiometabolic data including fasting blood glucose (FBG), serum triglyceride (TG), total cholesterol (TC), body mass index (BMI), waist circumference (WC), and fat mass percentage (FMP) were collected and analyzed. Data regarding children's diet and their psychological state were also recorded by validated questionnaires. Mean of continuous variables were compared by one-way ANOVA and correlations between continuous variables were determined by the Pearson correlation test. After excluding cases with missing data, information for 746 children (58 percent boys) and their parents was analyzed. Among children, TG was significantly correlated with BMI, WC, and FMP (p=0.001, r=0.24; p<0.0001, r=0.25; and p=0.01, r=0.19, respectively). Additionally, TC was significantly correlated with WC (p= 0.02). There were significant correlations between mother's FBG with children's BMI and WC (p=0.01, r=0.27; and p=0.00, r=0.29, respectively). Children of fathers and mothers with high BMI had significantly increased TC (p=0.04, and p=0.02, respectively). There was an inverse significant correlation between mood score and systolic blood pressure (p=0.03). There were also correlations between carbohydrates in children's diets and WC (p=0.02, r=0.34), and a near significant inverse correlation between nut consumption in diet and TC (p=0.05, r= -0.22). The current study showed the association of various factors on cardiometabolic risk factors in children and the relationship between these factors in children and in their parents. In addition to genetic predisposition, the familial aggregation of anthropometric measures underscores the role of obesogenic families in the development of cardiometabolic risk factors.
Notes : Print
descriptor : Metabolic Diseases
: Coronary Artery Disease- control and prevention
: Risk Factors
: Life Style
Originating Source : IRIsfahan University of Medical Sciences
publication type : p
Source : Vice Chancellery for Research
Ended Date : 2012
Project code : 185030
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Familial aggregation of the components of metabolic syndrome
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